Key Information Salary: Subject to comparable skills and experience. Future progression is based on annual performance review.
Duration of Contract : Fixed term for 12 months in the first instance
Hours per week : 35 hours per week (Full Time)
Closing Date : 23 September 2025
Summary of Role The Institute of Cancer Research is looking for a Clinical Trials Manager to join The Drug Development Unit (DDU) at its Sutton site in Surrey to work within the unit's investigator-sponsored studies team.
The successful applicant will be responsible for the day-to-day management of allocated Phase I clinical trials to ensure successful and timely trial delivery ensuring compliance with GCP and UK Clinical Trials legislation.
Key Requirements You should be a graduate in a life science or health related subject and have an understanding of Good Clinical Practice and the drug development process. This post is an excellent opportunity for an enthusiastic and well-motivated person to work in the largest academic Drug Development Unit in Europe. Excellent interpersonal skills are required, as is the ability to work to high standards across a variety of tasks with constant regard to scientific and regulatory requirements.
Minimum of a first degree or equivalent qualification in biomedical sciences or an allied subject (including health care disciplines).
Department/Directorate Information This position is within the Investigator Initiated Trial Team of the joint ICR/RM Drug Development Unit.
The Drug Development Unit, led by Professor Johann de Bono aims to seamlessly integrate preclinical drug discovery, proof-of-principle phase I trials and tumour-specific evaluation of novel agents. It is a conduit for the two-way communication between laboratory and clinical teams that is so essential for successful modern drug development. The unit conducts first-in-man phase I trials involving a range of targets, including growth factor or intracellular signalling, angiogenesis, apoptosis, epigenetics and DNA repair. All trials are underpinned by extensive analysis of biomarkers, both predictive and pharmacodynamics. The DDU includes The Oak Foundation Drug Development Centre (Oak Ward) housed within The Royal Marsden at the Sutton site and specifically designed for phase I clinical trials. Opened in February 2005, the centre provides 10 inpatient beds, five treatment chairs and two outpatient suites, and allows researchers to enter almost 300 patients onto phase I trials each year. This makes the unit one of the largest of its kind in the world.
The DDU also has portfolio of investigator-initiated trials of novel targeted agents and combinations of these, working with the ECMC network across the UK and with other Phase I units internationally. These studies are centrally managed by a dedicated team within the DDU that performs those functions associated with sponsoring early phase trials including project management, monitoring, pharmacovigilance, database development and central data review. The successful applicant will be responsible for the day-to-day management of allocated Phase I clinical trials to ensure successful and timely trial delivery ensuring with GCP and UK Clinical Trials legislation.
To apply for this post, please submit an online application including a supporting statement, detailing reasons why you are applying for the post and with your CV. We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact the recruiting team by email on [email protected]
Due to the high volumes of applications we receive, we reserve the right to close the advert before the published closing date once we have received a sufficient number of applications. Therefore, we advise that you to submit your application, as early as possible to avoid disappointment
About The Institute of Cancer Research Why work for us? As a member of staff, you'll have exclusive access to a range of staff benefits.
The ICR is committed to supporting overseas applicants applying for roles, please click here to find out further information.
The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found here.
We look forward to receiving applications from all candidates, wherever in the world they are currently based. We will select those who display the potential to become, or to support, the world leading cancer researchers of the future based on their application and performance at interview. However, we particularly welcome British applicants from black and ethnic minority backgrounds, as they are under-represented within the ICR and nationwide in STEM roles.