Senior Liver Cell Scientist- Research Scientist

King's College Hospital NHS Foundation Trust is one of the UK's largest and busiest teaching Trusts with a turnover of c£1.8 billion, 1.5 million patient contacts a year and more than 15,000 staff based across 5 main sites in South East London. The Trust provides a full range of local hospital services across its different sites, and specialist services from King's College Hospital (KCH) sites at Denmark Hill in Camberwell and at the Princess Royal University Hospital (PRUH) site in the London Borough of Bromley.

We encourage all our staff to have a healthy work/life balance. In doing so, you can apply for flexible working from the beginning of your employment. We offer a range of options which are designed to suit different circumstances and priorities in line with service requirements.

flexible-working

Job overview

The post holder is a member of a multidisciplinary team developing the use of hepatocyte transplantation in children with liver-based metabolic disorders. They will be based at the Institute of Liver Studies laboratories within the Cheyne Wing at King's College Hospital.

The post holder shall work on research project which aims to explore the immunomodulatory and regenerative potential of MSCs, with the goal of developing advanced therapy medicinal products (ATMPs) for clinical translation.

Main duties of the job

1. Conduct independent research into the immunomodulatory effects and therapeutic mechanisms of MSCs in biliary atresia models.

2. Employ a range of cellular and molecular techniques, including flow cytometry, ELISA, and advanced microscopy.

3. Collaborate closely with other researchers within the Hepatocyte Biology and Transplantation Group and with clinical partners.

4. Present work at weekly research meetings and contribute to publications, grant applications, and conference presentations.

5. Support junior researchers and students, providing scientific advice and training where appropriate.

6. Participate in GMP-compliant cell isolation and processing where required

7. Engage with the broader scientific and clinical community through lectures, seminars, and journal clubs

Working for our organisation

The Trust provides a full range of local and specialist services across its five sites. The trust-wide strategy of Strong Roots, Global Reach is our Vision to be BOLD, Brilliant people, Outstanding care, Leaders in Research, Innovation and Education, Diversity, Equality and Inclusion at the heart of everything we do. By being person-centred, digitally-enabled, and focused on sustainability, we aim to take Team King's to another level.

We are at a pivotal point in our history and we require individuals who are ready to join a highly professional team and make a real, lasting difference to our patients and our people.

King's is committed to delivering Sustainable Healthcare for All via our Green Plan. In line with national Greener NHS ambitions, we have set net zero carbon targets of 2040 for our NHS Carbon Footprint and 2045 for our NHS Carbon Footprint Plus. Everyone's contribution is required in order to meet the goals set out in our Green Plan and we encourage all staff to work responsibly, minimising their contributions to the Trust's carbon emissions, waste and pollution wherever possible.

Detailed job description and main responsibilities

General

• The post holder has a general duty of care for their own health, safety and wellbeing and that of work colleagues, visitors and patients within the hospital, in addition to any specific risk management or clinical governance accountabilities associated with this post.
• To observe the rules, policies, procedures and standards of King's College Hospital NHS Foundation Trust together with all relevant statutory and professional obligations.
• We want to be an organisation where everyone shares a commitment to delivering the very best care and feels like their contribution is valuable and valued.
• At King's we are a kind, respectful team:

Kind . We show compassion and understanding and bring a positive attitude to our work

Respectful . We promote equality, are inclusive and honest, speaking up when needed

Team . We support each other, communicate openly, and are reassuringly professional

• To observe and maintain strict confidentiality of personal information relating to patients and staff.
• To be responsible, with management support, for their own personal development and to actively contribute to the development of colleagues.
• This job description is intended as a guide to the general scope of duties and is not intended to be definitive or restrictive. It is expected that some of the duties will change over time and this description will be subject to review in consultation with the post holder.
• All employees must hold an 'nhs.net' email account which will be the Trust's formal route for email communication.
• Everyone is responsible for promoting inclusion no matter their role or team. At King's, we want to create an environment where everyone feels valued, respected and welcomed

Safe Guarding

The Trust takes the issues of Safeguarding Children, Adults and addressing Domestic Abuse very seriously. All employees have a responsibility to support the organisation in our duties by;

• attending mandatory training on safeguarding children and adults
• familiarising themselves with the Trust's processes for reporting concerns
• reporting any safeguarding child or adult concerns appropriately

Infection Control Statement

The post holder has an important responsibility for and contribution to infection control and must be familiar with the infection control and hygiene procedures and requirements when in clinical areas.

The post holder has an important responsibility for and contribution to make to infection control and must be familiar with the infection control and hygiene requirements of this role.

These requirements are set out in the National Code of Practice on Infection Control and in local policies and procedures which will be made clear during your induction and subsequent refresher training. These standards must be strictly complied with at all times.

Person specification

Qualifications

Essential criteria

• PhD in Cell Biology/ Immunology or equivalent experience.
• Proven experience with cell-based assays, immunoassays (e.g. ELISA), and flow cytometry and cell therapy research, ideally with MSC biology or translational applications

Desirable criteria

• in GMP-compliant cell isolation and processing where required

IMPORTANT

• Check your email account regularly as this is how we will communicate with you
• If you delete the job from any of your accounts, you may be prevented from accessing further communications
• To enquire about your application or inform us of any changes in your circumstances, please contact the named person on this advert
• Please provide email addresses for referees where possible
• Click here to see the range of benefits we offer
• Please review the documentation on our recruitment microsite, particularly the Trust's criminal records checking policy
• All staff have a responsibility for safeguarding children and vulnerable adults and for ensuring they are aware of the specific duties relating to their role.
• Please note that the closing date is given as a guide. On occasion, we might close a vacancy early due to a high number of applications being received. You are advised to submit your application as early as possible to avoid disappointment.

King's College Hospital NHS Foundation Trust Annual Reports and Other Corporate Publications

King's Health Partners Academic Health Science Centre Website

King's College Hospital is part of King's Health Partners Academic Health Sciences Centre (AHSC), a pioneering collaboration between King's College London, and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts.

Employer certification / accreditation badges

Documents to download

• JD Band 7 Liver Cell Scientist (PDF, 496.3KB)
• Denmark Hill Site Map (PDF, 1.2MB)
• Visa and Sponsorship Information (PDF, 344.6KB)
• Pay bands and pay points from 1 April 2025 (PDF, 44.6KB)