MRC Postdoctoral Research Scientist (Computational) Developmental Epigenetics

MRC Postdoctoral Research Scientist (Computational)

Developmental Epigenetics

Salary: £41,344 plus London allowances £5,385 per annum*

Fixed term (2 years)

London, UK

About us

The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS is one of three directly funded MRC research institutes and enjoys close links with our partners at Imperial College London and at the Imperial College Healthcare NHS Trust.

About the role

Join a dynamic team at the forefront of epigenomics research, where your computational skills will help unravel the complexities of gene regulation in development and disease. This position focuses on computational analysis and method development for large-scale multiomics datasets, particularly those derived from single-cell, spatial, and 3D genome experiments in a variety of disease and developmental systems, such as, gametogenesis and early embryonic development. The successful candidate will work closely with experimental collaborators, contribute to the development of reproducible analytical pipelines, and explore new computational frameworks for integrating diverse data types. There will be opportunities to lead independent projects and co-supervise students.

About you

We’re looking for a passionate and creative computational scientist ready to tackle big questions in genome biology to join the Developmental Epigenomics group. The group, led by Juanma Vaquerizas, combines cutting-edge genomics with innovative computational approaches to understand how the genome is regulated during development and affected in disease. The ideal candidate will have proven experience in single-cell omics data analysis and visualisation, proficiency in Python and/or R and experience with statistical analysis, machine learning methods, and high-performance computing.

What we offer

As well as the exciting opportunities this role presents, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits

How to apply

For full details of the post and to complete an online application, visit and upload your CV, names and contacts of two scientific references along with a cover letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be accepted. We welcome applications from candidates of all backgrounds and are committed to fostering a diverse and inclusive research environment. Please quote reference number LMS 2664.

Applicants are encouraged to review our LMS website for additional positions in developmental epigenetics.

The final appointment will be subject to pre-employment screening

Please note that applications may be reviewed by both LMS and Imperial staff

Closing date: 13 September 2025

*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two.