Postdoctoral Research Scientist

MRC Postdoctoral Research Scientist

Salary: £41,344 plus London allowances £5,385 per annum*

Fixed term (18 months)

London, UK

About us

The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS is one of three directly funded MRC research institutes and enjoy close links with our partners at Imperial College London and at the Imperial College Healthcare NHS Trust.

About the role

The Cellular Stress Group focuses on the role of AMP-activated protein kinase (AMPK) in the regulation of metabolism, with an interest in the therapeutic potential of AMPK activation in treating metabolic diseases. We are seeking an enthusiastic and ambitious Postdoctoral Research Scientist to join our group. The successful candidate will work on a project collaborating with AstraZeneca to investigate the role of AMPK activation in skeletal muscle cells. We are particularly interested in defining the role of AMPK complexes containing the muscle-specific g3 isoform.

About You

You will have a PhD (or equivalent experience) in biochemistry or a related field. You will have a strong background in biochemical, cellular and/or molecular biology techniques. Extensive cell culture expertise together with protein biochemical techniques (Western blotting, immunoprecipitation, enzyme assays) are essential. Previous experience working on protein kinase signalling and/or skeletal muscle metabolism would be an advantage. You should be highly motivated, committed and have clear career goals.

What we offer

As well as the exciting opportunities this role presents, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits

How to apply

For full details of this post and to complete an online application, visit our careers site and upload your CV, names and contacts of two scientific references along with a cover letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be accepted. Please quote reference number LMS 2630 .

*Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two, terms and conditions apply.

Closing date: 22 June 2025

The final appointment will be subject to pre-employment screening

Please note that applications may be reviewed by both LMS and Imperial staff