Process Development (UPSTREAM) Team Lead

Walker Cole International Ltd
London
Walker Cole International is hiring for an experienced Upstream Bioprocessing lead to join a growing biopharma company in West London and help mentor and grow their USP team.

You’ll lead a small team overseeing cell culture and upstream process development, optimising mammalian processes in ambr250 and small-scale bioreactors to support high-quality protein and antibody production.

Key responsibilities:

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Manage daily cell culture operations, including revival, subculture, cryopreservation, sampling, and in-process analysis.

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Monitor and optimise culture conditions, track outputs, and troubleshoot technical issues.

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Analyse data, report results, and maintain SOPs, risk assessments, COSHH, and DoEs.

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Collaborate with UK and international colleagues on process development projects.

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Ensure equipment is maintained and processes run efficiently.

You’ll need:

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Experience in mammalian cell culture process development, ideally using automated bioreactors.

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Knowledge of GLP/GMP standards, safety audits, and risk assessments.

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Understanding of therapeutic protein/antibody quality attributes.

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Strong communication, leadership, and problem-solving skills.

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A Masters or PhD in Biological Science or related field.

Cell Culture | Bioprocess Development | Bioreactors | Team Leadership | GMP | Antibody Production | Biosimilars | Upstream
Posted 2025-10-06

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