Process Development (UPSTREAM) Team Lead

Walker Cole International Ltd

London

Walker Cole International is hiring for an experienced Upstream Bioprocessing lead to join a growing biopharma company in West London and help mentor and grow their USP team.

You’ll lead a small team overseeing cell culture and upstream process development, optimising mammalian processes in ambr250 and small-scale bioreactors to support high-quality protein and antibody production.

Key responsibilities:

Manage daily cell culture operations, including revival, subculture, cryopreservation, sampling, and in-process analysis.

Monitor and optimise culture conditions, track outputs, and troubleshoot technical issues.

Analyse data, report results, and maintain SOPs, risk assessments, COSHH, and DoEs.

Collaborate with UK and international colleagues on process development projects.

Ensure equipment is maintained and processes run efficiently.

You’ll need:

Experience in mammalian cell culture process development, ideally using automated bioreactors.

Knowledge of GLP/GMP standards, safety audits, and risk assessments.

Understanding of therapeutic protein/antibody quality attributes.

Strong communication, leadership, and problem-solving skills.

A Masters or PhD in Biological Science or related field.

Posted 2025-10-06

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