Advance Therapy Product Translational Scientist

Job summary

The John Goldman Centre for Cellular Therapy based at Hammersmith Hospital is a HTA, JACIE and MHRA IMP/ATMP licensed facility that provides highly specialist clinical, technical and scientific services for Bone Marrow transplant patients.

Applications are invited from well-motivated and organised individuals who will be involved in all aspects of GMP clinical processing (including advanced ATMP protocols and cell culture), flow cytometry and other quality testing.

The Advanced Therapy Product Translational Scientistwill additionally be the lead in service developments such as ATMP validations, introduction of new techniques into the laboratory, quality system development, training, data management, assisting new/on-going translational research, handling commercially approved ATMP for clinical application, assisting in Clinical trials approval and bringing new therapies into clinical practice.

Applicants must have HCPC registration, minimum of an MSC level qualification with practical experience of GMP ATP manufacture / development or handling. Applicants should have direct experience in this field or in a related area such as Blood Transfusion, Immunology or ATP development under GMP conditions. In order to meet the needs of a high-quality service, the post holder is expected to be flexible in their working arrangements and be able to demonstrate the ability to work consistently under pressure to the highest standards.

Main duties of the job

To work with the Clinical Trials Lead and JGCCT Director to ensure that the JGCCT is ready to successfully delivery Advanced Therapy Medicinal Products (ATMPs) and Advanced Therapy Medicinal Investigational Products (ATMIPs) both within clinical trial and clinical practice setting.

To engage with all relevant stakeholders (internal and external) such as ATMP manufacturer(s), Pharmacy Clinical Trials & ATMPs and NHS clinical and research staff, Novel Activity and other relevant committees as applicable within the context of ATMP/ATIMPs provision at the Trust.

To develop and maintain all necessary standard operating procedures, documents, labels and guidelines in relation to ATMPs in conjunction with Pharmacy Clinical Trials & ATMP staff.

Lead laboratory ATMP manufacture and testing ready for clinical use.

Help monitor the clinical trial activity and reimbursement charges for the JGCCT.

About us

At Imperial College Healthcare you can achieve extraordinary things with extraordinary people, working with leading clinicians pushing boundaries in patient care.

Become part of a vibrant team living our values - expert, kind, collaborative and aspirational. You'll get an experience like no other and will fast forward your career.

Benefits include career development, flexible working and wellbeing, staff recognition scheme. Make use of optional benefits including Cycle to Work, car lease schemes, season ticket loan or membership options for onsite leisure facilities.

We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part time or job share. Please talk to us at interview.

Job description

Job responsibilities

To work with the Clinical Trials Lead and JGCCT Director to ensure that the JGCCT is ready to successfully delivery Advanced Therapy Medicinal Products (ATMPs) and Advanced Therapy Medicinal Investigational Products (ATMIPs) both within clinical trial and clinical practice setting.

Refer to the Job Description for detailed duties and responsibilities.

Job description
Job responsibilities

To work with the Clinical Trials Lead and JGCCT Director to ensure that the JGCCT is ready to successfully delivery Advanced Therapy Medicinal Products (ATMPs) and Advanced Therapy Medicinal Investigational Products (ATMIPs) both within clinical trial and clinical practice setting.

Refer to the Job Description for detailed duties and responsibilities.

Person Specification

Education / Qualification

Essential

• MSc in appropriate specialist subject
• Health and Care Professions Council registration or Equivlent
• Good Manufacturing Practice (GMP) training/course.

Desirable

• Quality Management course.
• GCP Training

Experience

Essential

• Minimum 2 years' experience in Blood Transfusion Science, Immunology or ATMP development laboratory with GMP
• Commercial ATMP handling

Desirable

• Experience working in Grade B clean room production environment
• Experience of HPC processing and HPC quality testing.
• ATMP / Clinical Trial process development experience
• Experience in liaising with multidisciplinary teams

Values and behaviours

Essential

• Proactive
• Good interpersonal and organisational skills
• Good communicator across diverse staff groups
• Team worker

Skills/knowledge/ abilities

Essential

• Excellent verbal and written communication skills
• Good ability to organise and prioritise work
• Technical aptitude
• Ability to work independently as well as in a team
• Problem solving skills

Physical Qualities

Essential

• Good general health /fitness to practice to enable to fulfil the requirements of the role

Person Specification
Education / Qualification

Essential

• MSc in appropriate specialist subject
• Health and Care Professions Council registration or Equivlent
• Good Manufacturing Practice (GMP) training/course.

Desirable

• Quality Management course.
• GCP Training

Experience

Essential

• Minimum 2 years' experience in Blood Transfusion Science, Immunology or ATMP development laboratory with GMP
• Commercial ATMP handling

Desirable

• Experience working in Grade B clean room production environment
• Experience of HPC processing and HPC quality testing.
• ATMP / Clinical Trial process development experience
• Experience in liaising with multidisciplinary teams

Values and behaviours

Essential

• Proactive
• Good interpersonal and organisational skills
• Good communicator across diverse staff groups
• Team worker

Skills/knowledge/ abilities

Essential

• Excellent verbal and written communication skills
• Good ability to organise and prioritise work
• Technical aptitude
• Ability to work independently as well as in a team
• Problem solving skills

Physical Qualities

Essential

• Good general health /fitness to practice to enable to fulfil the requirements of the role

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .
UK Registration

Applicants must have current UK professional registration. For further information please see

Additional information
Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the .

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. .
UK Registration

Applicants must have current UK professional registration. For further information please see

Employer details

Employer name

Imperial College Healthcare NHS Trust
Address

Hammersmith

Du Cane Road

London

W12 0HS

Employer's website